What lab tests may be helpful in the diagnosis of syndrome of inappropriate antidiuretic hormone secretion (SIADH)?

Updated: Aug 16, 2019
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

The following laboratory tests may be helpful in the diagnosis of SIADH:

  • Serum sodium, potassium, chloride, and bicarbonate

  • Plasma osmolality

  • Serum creatinine

  • Blood urea nitrogen

  • Blood glucose

  • Urine osmolality

  • Serum uric acid

  • Serum cortisol

  • Thyroid-stimulating hormone

  • Plasma AVP level

The patient’s volume should be assessed clinically to help rule out the presence of hypovolemia.


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