How is dialysis-related beta-2-microglobulin (beta-2m) amyloidosis treated?

Updated: Nov 14, 2019
  • Author: Anita Basu, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

At present, no adequate treatment of beta-2m amyloidosis exists. Medical therapy is limited to symptomatic approaches to ameliorating joint pain and inflammation. Conservative treatment includes physical and occupational therapy. Wrist splints, cervical collars, lumbar corsets, knee braces, and immobilization for spondyloarthropathies often are helpful.

The treatment of joint pain includes the use of the following:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Intra-articular injections of prednisolone
  • 10% hydrocortisone cream
  • Low-dose oral prednisone in severe cases

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