What is the clinical staging of beta-2-microglobulin (beta-2m) amyloidosis?

Updated: Nov 14, 2019
  • Author: Anita Basu, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Hoshino et al validated a clinical staging score to measure the severity of dialysis-related amyloidosis (DRA). [16] Elements of the score are as follows:

  • Polyarthralgia – 3 points
  • Dialysis-related spondyloarthropathy (DRS) – 3 points
  • Trigger finger – 2 points
  • Carpal tunnel syndrome – 2 points

DRA is staged according to the score as follows:

  • Mild (3-4 points)
  • Moderate (5-7 points)
  • Severe (8-10 points)

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