Which medications in the drug class Beta-Blockers, Nonselective are used in the treatment of Renovascular Hypertension?

Updated: Dec 01, 2020
  • Author: Rebecca J Schmidt, DO, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Beta-Blockers, Nonselective

Although selective beta1 -blockers (eg, metoprolol) are preferred over nonselective agents in patients with asthma or pulmonary conditions in which acute bronchospasm would put them at risk (eg, chronic obstructive pulmonary disease [COPD], emphysema, or bronchitis), all beta-blockers should be used with caution in these patients, particularly with high-dose therapy.

Propranolol (Inderal, InnoPran XL)

Propranolol is a beta-adrenergic blocking agent. Renin release is enhanced by beta-receptor activation, and chronic beta blockade consistently suppresses plasma renin activity. Propranolol has membrane-stabilizing activity and decreases the automaticity of contractions. It is not suitable for emergency treatment of hypertension and should not be administered IV in hypertensive emergencies.

Labetalol (Trandate)

Labetalol blocks beta1-adrenergic, alpha-adrenergic, and beta2-adrenergic receptor sites.

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