Which medications in the drug class Cardiovascular, Other are used in the treatment of Renovascular Hypertension?

Updated: Dec 01, 2020
  • Author: Rebecca J Schmidt, DO, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Cardiovascular, Other

Renin inhibitors constitute the newest class of antihypertensive drugs. They act by disrupting the RAAS feedback loop.

Aliskiren (Tekturna)

Aliskiren is a direct renin inhibitor. It decreases plasma renin activity and inhibits the conversion of angiotensinogen to angiotensin I (thus also decreasing angiotensin II) and thereby disrupts the RAAS feedback loop. Aliskiren is indicated for treatment of hypertension, either alone or in combination with other antihypertensive drugs.


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