Which drugs are used to treat blood pressure in autosomal dominant polycystic kidney disease (ADPKD?)

Updated: Mar 24, 2020
  • Author: Roser Torra, MD, PhD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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The drugs of choice for this condition are angiotensin-converting enzyme (ACE) inhibitors (eg, captopril, enalapril, lisinopril) or angiotensin II receptor blockers (ARBs) such as telmisartan, losartan, irbesartan, and candesartan. These agents remain the most recommended drugs to treat hypertension in patients with ADPKD, although studies of the renin-angiotensin-aldosterone system have not convincingly demonstrated that it plays an important role in its pathogenesis. [43] Calcium channel blockers are not recommended.

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