How is metabolic alkalosis treated in syndrome of apparent mineralocorticoid excess (AME)?

Updated: Dec 10, 2020
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
  • Print

Metabolic alkalosis in the syndrome of AME may be treated with potassium-sparing diuretics. On the other hand, dexamethasone may be used to suppress cortisol production by inhibiting ACTH. Unlike cortisol and some synthetic glucocorticoids, dexamethasone does not activate the mineralocorticoid receptor.

Did this answer your question?
Additional feedback? (Optional)
Thank you for your feedback!