Why is treatment of chronic metabolic acidosis indicated in patients with chronic kidney disease (CKD)?

Updated: Dec 08, 2020
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Treatment of chronic metabolic acidosis in persons with chronic kidney disease (CKD) is indicated because it can help to prevent bone loss that can progress to osteopenia or osteoporosis. In children, growth retardation can occur. In addition, treatment slows the progression of hyperparathyroidism and helps to reduce the high-protein catabolic state associated with uremic acidosis, which leads to loss of muscle mass and malnutrition.

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