How is the risk of hypernatremia and hyperosmolality minimized in the treatment of metabolic acidosis?

Updated: Oct 10, 2018
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

To minimize the risk of hypernatremia and hyperosmolality, two 50-mL ampules of 8.4% NaHCO3 (containing 50 mEq each) are added to 1 L of 0.25 normal saline or three ampules are added to 1 L of 5% dextrose in water.


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