How does infusion of acids cause non-anion gap (AG) (hyperchloremic) metabolic acidosis?

Updated: Oct 10, 2018
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

The addition of an acid that contains Cl- as an ion (eg, NH4 Cl) can result in a normal-AG acidosis because the drop in HCO3- is accompanied by an increase in Cl-.

The use of arginine or lysine hydrochloride as amino acids during hyperalimentation can have the same result.


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