How does hypobicarbonatemia increase the risk of developing metabolic acidosis?

Updated: Dec 08, 2020
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Note that patients with hypobicarbonatemia from renal failure cannot compensate for additional HCO3- loss from an extrarenal source (eg, diarrhea) and severe metabolic acidosis can develop rapidly.

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