What is the role of the urine sodium to chloride ratio in the workup of hypokalemia (low potassium level)?

Updated: Dec 06, 2018
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Wu et al reported that urinary levels of sodium (Na+) and chloride (Cl-) were high and coupled (Na+: Cl- ratio ∼1) in patients with renal tubular disorders and those using diuretics, but urinary Na+: Cl- ratios were skewed or uncoupled in patients with anorexia/bulimia nervosa (5.0 ± 2.2) and in patients abusing laxatives (0.4 ± 0.2). [47]


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