What are the signs and symptoms of Bartter syndrome?

Updated: Dec 06, 2018
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

The most severe cases of Bartter syndrome manifest antenatally or neonatally as profound volume depletion and hypokalemia. Patients with less severe cases present in childhood or early adulthood with persistent hypokalemic metabolic alkalosis that is resistant to replacement therapy. In general, however, onset of true Bartter syndrome occurs by age 5 years.


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