What causes increased potassium excretion?

Updated: Dec 06, 2018
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Increased excretion of potassium, especially coupled with poor intake, is the most common cause of hypokalemia. Increased potassium excretion may result from any of the following:

  • Mineralocorticoid excess (endogenous or exogenous)

  • Hyperreninism from renal artery stenosis

  • Osmotic diuresis: Mannitol and hyperglycemia can cause osmotic diuresis

  • Increased gastrointestinal losses

  • Drugs

  • Genetic disorders

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