Which factors regulate the distribution of potassium between intracellular and extracellular space?

Updated: Dec 06, 2018
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Several factors regulate the distribution of potassium between the intracellular and extracellular space, as follows:

  • Glycoregulatory hormones: (1) Insulin enhances potassium entry into cells, and (2) glucagon impairs potassium entry into cells

  • Adrenergic stimuli: (1) Beta-adrenergic stimuli enhance potassium entry into cells, and (2) alpha-adrenergic stimuli impair potassium entry into cells

  • pH: (1) Alkalosis enhances potassium entry into cells, and (2) acidosis impairs potassium entry into cells


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