Which medications in the drug class Calcium are used in the treatment of Hypocalcemia?

Updated: Aug 08, 2019
  • Author: Manish Suneja, MD, FASN, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Calcium

Intravenous calcium chloride or gluconate infusions restore serum calcium levels. Calcium chloride delivers 3 times more elemental calcium than calcium gluconate.

Calcium chloride

Calcium chloride moderates nerve and muscle performance by regulating the action potential excitation threshold. This form of calcium is preferred for patients in cardiac arrest and in other serious cases.. The 10% IV solution provides 100 mg/mL of calcium chloride equaling 27.2 mg/mL (1.4 mEq/mL) of elemental calcium (ie, 10 mL of calcium chloride 10% solution contains 272 mg of elemental calcium).

Calcium gluconate (Cal-GLU)

Calcium gluconate moderates nerve and muscle performance and facilitates normal cardiac function. It is the preferred form of calcium for patients not in cardiac arrest. One ampule contains 93 mg of elemental calcium. After IV treatment, calcium levels can usually be maintained with a high-calcium diet, although some patients also require oral calcium supplementation.

The oral formulation is usually used as supplementation to IV calcium therapy. Amounts of elemental calcium in calcium gluconate are as follows:

• 500-mg tablet: 45 mg

• 650-mg tablet: 58.5 mg

• 975-mg tablet: 87.75 mg

• 1-g tablet: 90 mg

Calcium carbonate (Oystercal, Caltrate, Oysco 500, Tums E-X, Children's Pepto)

Calcium carbonate is indicated to restore and maintain normocalcemia when hypocalcemia is not severe enough to warrant rapid replacement. It is used orally as supplementation to IV calcium therapy. Calcium carbonate moderates nerve and muscle performance by regulating the action potential excitation threshold. Amounts of elemental calcium in calcium carbonate tablets are as follows: Tums, 200 mg; Rolaids, 220 mg; Os-Cal, 500 mg

Calcium citrate (Calcitrate, Cal-Citrate 225, Cal-Cee)

Calcium citrate is an oral formulation usually used as supplementation to IV calcium therapy. Calcium moderates nerve and muscle performance by regulating the action potential excitation threshold and facilitating normal cardiac function. Give the amount needed to supplement dietary intake, so as to reach recommended daily amounts. The amount of elemental calcium in 1000 mg of calcium citrate is 210 mg.


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