What is the incidence of hypocalcemia in the US?

Updated: Aug 08, 2019
  • Author: Manish Suneja, MD, FASN, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Epidemiologic studies of hypocalcemia versus other electrolyte abnormalities have not been performed. During the last 20 years, laboratory tests have quantified serum and ionized calcium and PTH levels, enabling easier diagnosis. The incidence of ionized hypocalcemia is difficult to quantify. In intensive care patients, reported rates have ranged from 15-88%. [33] A systematic review and meta-analysis of hypocalcemia after thyroidectomy found that the median incidence of transient hypocalcaemia was 27% (range, 19-38%) and that of permanent hypocalcemia was 1% (range, 0-3%). [34]   In a series of 500 postsurgical patients operated on for hyperparathyroidism, 2% had permanent hypocalcemia. [35]

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