What is the safety of febuxostat in the treatment of hyperuricemia?

Updated: Aug 31, 2018
  • Author: James W Lohr, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Overall, febuxostat was as safe as allopurinol in the CONFIRMS trial. [30] However, previous studies have identified cardiovascular events with febuxostat, and large ongoing trials are comparing the cardiovascular safety of febuxostat versus allopurinol. [31]


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