Who are the ideal candidates for allopurinol treatment of chronic gout and hyperuricemia?

Updated: Aug 31, 2018
  • Author: James W Lohr, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

The ideal candidates for allopurinol treatment are as follows:

  • Uric acid overproducers (24-h urinary uric acid excretion >800 mg on general diet or >600 mg on a purine-restricted diet)
  • Patients with renal insufficiency, nephrolithiasis, or tophaceous gout
  • Patients at risk for developing uric acid nephropathy

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