What is the mortality rate of hyperuricemia?

Updated: Aug 31, 2018
  • Author: James W Lohr, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Although observational studies on hyperuricemia and stroke have yielded conflicting results, a meta-analysis by Li et al concluded that hyperuricemia may modestly increase the risk of stroke incidence and mortality. [19] The authors reviewed 15 studies that together included 22,571 cases of stroke and 1,042,358 participants. The risk ratio (RR) for the incidence of stroke in patients with hyperuricemia was 1.22 (95% CI, 1.02-1.46) and the RR for mortality was 1.33 (95% CI, 1.24-1.43). The pooled estimate of multivariate RRs of both stroke incidence and mortality were higher in women than in men (1.25 vs 1.08 and 1.41 vs 1.26, respectively). [19]


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