Which medications in the drug class Antihypertensives, Other are used in the treatment of Hypertension?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Antihypertensives, Other

Reserpine is a peripherally acting adrenergic agent. It is indicated for mild hypertension and can be used as adjunctive therapy with other antihypertensive agents in more severe forms of hypertension.


Reserpine reduces blood pressure by depleting sympathetic biogenic amines. The result of reserpine's effects on biogenic amines is sympathetic dysfunction, with a subsequent decrease in peripheral vascular resistance and a lowering of blood pressure often associated with bradycardia. This agent is also associated with depression.

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