What is the preferred antihypertensive medication for use in pregnant women?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Answer

Although reducing maternal risk is the goal of treating chronic hypertension in pregnancy, fetal safety largely directs the choice of antihypertensive agent. Methyldopa is generally the preferred first-line agent because of its safety profile. [5, 126]  Other drugs that may be considered include labetalol, beta-blockers, and diuretics. [7] ACOG does not recommend the use of any of the following [142] :

  • ACEIs
  • ARBs
  • Renin inhibitors
  • Mineralocorticoid receptor antagonists

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