How is a diagnosis of hyperaldosteronism confirmed?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Answer

The diagnosis of primary hyperaldosteronism can be confirmed by the determination of the aldosterone excretion rate in a 24-hour urine following IV or oral salt loading (ie, urinary aldosterone excretion rate greater than 12-14 μg/24 hours, with urine sodium at least 200 mEq/24 hours). Saline suppression testing can also be used to confirm the diagnosis.


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