How can secondary causes be excluded when diagnosing resistant hypertension (high blood pressure)?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Answer

Whenever confronted with resistant hypertension, try to exclude any secondary causes of hypertension. A reevaluation of the patient’s history, physical examination, and laboratory results may provide clues to secondary hypertension (eg, renal parenchymal disease, renal artery stenosis, primary hyperaldosteronism, obstructive sleep apnea, pheochromocytoma/paraganglioma, Cushing syndrome, coarctation of the aorta). [42] Primary hyperaldosteronism is estimated to have a prevalence of 20% in this population. [119]


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