Is baseline hypertension (high blood pressure) an independent predictor of incident diabetes mellitus (DM)?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Answer

In a study that evaluated BP pattern changes during the development of hypertension in patients with or without diabetes mellitus using data from the Mexico City Diabetes Study (MCDS) and the Framingham Offspring Study (FOS), investigators found that although baseline diabetes mellitus was a significant predictor of incident hypertension, baseline hypertension was an independent predictor of incident diabetes mellitus. They indicated that development of hypertension and diabetes mellitus track each other over time; transition from normotension to hypertension was characterized by a sharp increase in BP values; and insulin resistance was not only a common feature of prediabetes and prehypertension, but it was also an antecedent of progression to the two respective disease states. [94]


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