What are the Coronary Artery Risk Development in Young Adults (CARDIA) prediction model criteria and how effective are they?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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In an analysis of 4388 patients enrolled in the Coronary Artery Risk Development in Young Adults (CARDIA) study, a prediction model based on Framingham Heart Study criteria was better than prehypertension at identifying young adults who went on to develop new hypertension in the following 25 years. The c index for incident hypertension was 0.84 using the Framingham prediction model and 0.71 using prehypertension. [64, 65]

Criteria used in the CARDIA prediction model included age, sex, body mass index (BMI), smoking, systolic blood pressure (BP), and parental history of hypertension. Prehypertension was defined as systolic BP 120-139 mm Hg or diastolic BP 80-89 mm Hg.

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