What are the benefits of successful antihypertensive therapy?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Answer

Clinical trials have demonstrated the following benefits with antihypertensive therapy [5] :

  • Average 35-40% reduction in stroke incidence

  • Average 20-25% reduction in myocardial infarction

  • Average >50% reduction in heart failure

Moreover, it is estimated that 1 death is prevented per 11 patients treated for stage 1 hypertension and other cardiovascular risk factors when a sustained reduction of 12 mm Hg in systolic BP over 10 years is achieved. [5] However, for the same reduction is systolic BP reduction, it is estimated that 1 death is prevented per 9 patients treated when cardiovascular disease or end-organ damage is present. [5]


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