Which specific drug class recommendations are made based on comorbidities of hypertension (high blood pressure)?

Updated: Feb 22, 2019
  • Author: Matthew R Alexander, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Compelling indications for specific agents include comorbidities such as heart failure, ischemic heart disease, chronic kidney disease, and diabetes. Drug intolerability or contraindications may also be factors. [5]

The following are drug class recommendations for compelling indications based on various clinical trials [5] :

  • Heart failure: Diuretic, beta-blocker, ACE inhibitor/ARB, aldosterone antagonist

  • Following myocardial infarction: Beta-blocker, ACE inhibitor

  • Diabetes: ACE inhibitor/ARB

  • Chronic kidney disease: ACE inhibitor/ARB

See Treatment and Medication for more detail.

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