How can hyperkalemia (high serum potassium level) be prevented?

Updated: Apr 09, 2020
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Inform patients at risk for hyperkalemia about dietary sources of potassium, including salt substitutes. Adjust the diet to decrease potassium dietary load. Adjust medications that predispose to or exacerbate hyperkalemia.

In a retrospective observational study of 27,355 patients with diabetes, Raebel et al concluded that potassium monitoring can reduce the incidence of serious hyperkalemia-associated adverse events in patients with diabetes and chronic kidney disease who are undergoing renin-angiotensin-aldosterone system inhibitor therapy. [16] The investigators found that for monitored patients with diabetes alone, the adjusted relative risk was 0.50, whereas for monitored patients who also had chronic kidney disease, the adjusted relative risk was 0.29.

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