What supplemental tests may be useful in the evaluation of hyperkalemia (high serum potassium level)?

Updated: Apr 09, 2020
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Depending on the clinical findings and the results of the above laboratory work, the following may be indicated:

  • Glucose level - In patients with known or suspected diabetes mellitus

  • Digoxin level - If the patient is on a digitalis medication

  • Arterial or venous blood gas - If acidosis is suspected

  • Urinalysis - If signs of renal insufficiency without an already known cause are present (to look for evidence of glomerulonephritis)

  • Serum cortisol and aldosterone levels - To check for mineralocorticoid deficiency when other causes are eliminated

  • Serum uric acid and phosphorus assays - For tumor lysis syndrome

  • Serum creatinine phosphokinase (CPK) and calcium measurements - For rhabdomyolysis

  • Urine myoglobin test - For crush injury or rhabdomyolysis; suspect if urinalysis reveals blood in the urine but no red blood cells are seen on urine microscopy

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