Which disorders cause type IV renal tubular acidosis, resulting in hyperkalemia (high serum potassium level)?

Updated: Jun 20, 2018
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Disorders that can cause type IV renal tubular acidosis, resulting in hyperkalemia, include the following:

  • Diabetes mellitus
  • Sickle cell disease or trait
  • Lower urinary tract obstruction
  • Adrenal insufficiency
  • Primary Addison syndrome due to autoimmune disease, tuberculosis, or infarct
  • Enzyme deficiencies
  • Genetic disorders (see below)

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