What is the prevalence of hyperparathyroidism in patients with hypercalcemia?

Updated: Oct 03, 2018
  • Author: Mahendra Agraharkar, MD, MBBS, FACP, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Some studies suggest that up to 20% of patients who present to the ED with hypercalcemia are ultimately diagnosed with hyperparathyroidism. Royer et al performed a retrospective review from 2012 to 2013 of patients with hypercalcemia in the ED, and a definitive diagnosis of hyperparathyroidism was identified in 3.5% (6 of 168). According to the authors, 24% (41 of 168) identified with mild hypercalcemia were discharged from the ED with no definitive follow-up plan, and although mild hypercalcemia found during ED workup rarely requires immediate medical treatment, many of those patients may have hyperparathyroidism amenable to surgical correction. The authors therefore suggested that an appropriate mechanism for outpatient hypercalcemia workup should be integrated into the patient's ED discharge plan. [10]

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