Which physical findings are characteristic of Goodpasture syndrome (anti–glomerular basement membrane disease) (anti-GBM)?

Updated: Dec 16, 2020
  • Author: Pranay Kathuria, MD, FACP, FASN, FNKF; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Physical examination findings in patients with anti-GBM disease include the following:

  • Tachypnea
  • Inspiratory crackles over lung bases
  • Cyanosis
  • Hepatosplenomegaly (may be present)
  • Hypertension (present in 20% of cases)
  • Rash
  • Edema

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