Which medications in the drug class Beta-Blockers, Beta-1 Selective are used in the treatment of Chronic Glomerulonephritis?

Updated: Feb 24, 2020
  • Author: Moro O Salifu, MD, MPH, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Beta-Blockers, Beta-1 Selective

Beta-adrenergic blockers compete with beta-adrenergic agonists for available beta-receptor sites. These agents inhibit mainly beta1 receptors (located mainly in cardiac muscle).

Metoprolol (Lopressor, Toprol XL)

Metoprolol is a selective beta1-adrenergic blocker that decreases the automaticity of contractions. During intravenous (IV) administration, carefully monitor blood pressure, heart rate, and electrocardiographic readings.

Bisoprolol (Zebeta)

Bisoprolol is a selective beta1-adrenergic receptor blocker that decreases automaticity of contractions.

Esmolol (Brevibloc)

Esmolol is an ultra–short-acting beta2-blocker. It is particularly useful in patients with labile arterial pressure, especially if surgery is planned, because it can be discontinued abruptly if necessary. It may be useful as a means to test beta-blocker safety and tolerance in patients with a history of obstructive pulmonary disease who are at possible risk of bronchospasm from beta-blockade. The elimination half-life of esmolol is 9 minutes.

Atenolol (Tenormin)

Atenolol selectively blocks beta-1 receptors with little or no effect on beta-2 receptors.


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