Which medications in the drug class Beta-Blockers, Nonselective are used in the treatment of Chronic Glomerulonephritis?

Updated: Feb 24, 2020
  • Author: Moro O Salifu, MD, MPH, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Beta-Blockers, Nonselective

Nonselective beta-blockers inhibit both beta1 receptors (located mainly in cardiac muscle) and beta2 receptors located in the bronchial and vascular musculature. These agents slow the sinus rate and decrease AV nodal conduction. Carefully monitor blood pressure.

Propranolol (Inderal LA, InnoPran XL)

Propranolol is a class II antiarrhythmic nonselective beta-adrenergic receptor blocker. It has membrane-stabilizing activity and decreases the automaticity of contractions.

Sotalol (Betapace, Sorine)

This class III antiarrhythmic agent blocks K+ channels, prolongs action potential duration (APD), and lengthens the QT interval. It is a non–cardiac selective beta-adrenergic blocker. Sotalol is shown to be effective in the maintenance of sinus rhythm, even in patients with underlying structural heart disease.

Labetalol (Trandate)

Labetalol blocks alpha-, beta1-, and beta2-adrenergic receptor sites, decreasing blood pressure.

Penbutolol

Pindolol has mild intrinsic sympathomimetic activity and negative chronotropic and inotropic effects.

Penbutolol (Levatol)

Penbutolol has mild intrinsic sympathomimetic activity and negative chronotropic and inotropic effects.


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