Which physical findings of diabetes mellitus (DM) suggest nephropathy?

Updated: Oct 09, 2019
  • Author: Vecihi Batuman, MD, FASN; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Generally, diabetic nephropathy is considered after a routine urinalysis and screening for microalbuminuria in the setting of diabetes. Patients may have physical findings associated with long-standing diabetes mellitus, such as the following:

  • Hypertension

  • Peripheral vascular occlusive disease (decreased peripheral pulses, carotid bruits)

  • Evidence of diabetic neuropathy in the form of decreased fine sensations and diminished tendon reflexes

  • Evidence of fourth heart sound during cardiac auscultation

  • Nonhealing skin ulcers/osteomyelitis

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