What is the role of systolic blood pressure in the progression of chronic kidney disease (CKD) to end-stage renal disease (ESRD)?

Updated: Oct 26, 2020
  • Author: Pradeep Arora, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

In a diverse, community-based study by Peralta et al, high SBP appeared to account for most of the risk of progression to ESRD. [62] The risk began at an SBP of 140 mm Hg, as opposed to the current recommended goal of less than 130 mm Hg. The highest risk was found among patients with an SBP of at least 150 mm Hg. These researchers concluded that to improve blood pressure control in CKD, treatment approaches that lower SBP may be required. [62]


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