What steps can be taken to delay or halt the progression of chronic kidney disease (CKD)?

Updated: Oct 26, 2020
  • Author: Pradeep Arora, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Measures indicated to delay or halt the progression of chronic kidney disease (CKD) are as follows:

  • Treatment of the underlying condition if possible
  • Aggressive blood pressure control to target values per current guidelines
  • Treatment of hyperlipidemia to target levels per current guidelines
  • Aggressive glycemic control per the American Diabetes Association (ADA) recommendations (target hemoglobin A1c [HbA1C] < 7%)
  • Avoidance of nephrotoxins, including intravenous (IV) radiocontrast media, nonsteroidal anti-inflammatory drugs (NSAIDs), and aminoglycosides
  • Use of renin-angiotensin system (RAS) blockers in patients with diabetic kidney disease (DKD) and proteinuria
  • Use of sodium–glucose cotransporter 2 (SGLT2) inhibitors 
  • Use of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin-receptor blockers (ARBs) in patients with proteinuria

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