What is the role of renal biopsy in the workup of azotemia?

Updated: Apr 24, 2020
  • Author: Moro O Salifu, MD, MPH, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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When glomerulonephritis, vasculitis, and (occasionally) interstitial nephritis are suspected, kidney biopsy is indicated to establish the correct diagnosis and guide therapy. The following are common indications for kidney biopsy:

  • Isolated glomerular proteinuria or hematuria
  • Nephrotic syndrome
  • Acute nephritic syndrome
  • Unexplained acute or subacute kidney injury

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