What is the role of renal biopsy in the workup of azotemia?

Updated: Sep 19, 2018
  • Author: Moro O Salifu, MD, MPH, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

When glomerulonephritis, vasculitis, and (occasionally) interstitial nephritis are suspected, renal biopsy is indicated to establish the correct diagnosis and guide therapy. The following are common indications for renal biopsy:

  • Isolated glomerular proteinuria or hematuria

  • Nephrotic syndrome

  • Acute nephritic syndrome

  • Unexplained acute or subacute renal failure


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