Which medications in the drug class Aldosterone Antagonists, Selective are used in the treatment of Proteinuria?

Updated: Mar 25, 2020
  • Author: Beje Thomas, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Aldosterone Antagonists, Selective

Patients with fluid overload should be treated with diuretics. Use a combination of diuretics acting at different sites of the nephron (eg, loop diuretic ± thiazide ± spironolactone). Aldosterone antagonists are used to lower the blood pressure and normalize serum potassium.

Spironolactone (Aldactone)

Spironolactone is the agent most commonly used to treat hyperaldosteronism because it directly antagonizes aldosterone effects at the distal tubule.


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