What is the role of urine dipstick and sulfosalicylic acid test (SSA) in the diagnosis of proteinuria?

Updated: Mar 25, 2020
  • Author: Beje Thomas, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

The urine dipstick detects albumin primarily. Albuminuria is seen in glomerular proteinuria. False-positive results can occur with recently exposure to iodinated radiocontrast agents, alkaline urine, and gross hematuria. SSA detects all proteins, not just albumin.  Proteinuria involving non-albumin proteins as well as albumin is seen more in tubular or overflow proteinuria. Iodinated radiocontrast also will interfere with the accuracy of the SSA test.


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