What are the options for detection of proteinuria?

Updated: Mar 25, 2020
  • Author: Beje Thomas, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Evaluation of proteinuria normally is conducted on an outpatient basis, unless the patient develops a complication of severe nephrotic syndrome. All patients with evidence of glomerular disease or any reduction in renal function should be referred to a nephrologist.

Integral to the process of evaluating for proteinuria is quantification of the total amount of protein spilling into the urine. The various methods to detect proteinuria include urine dipstick and sulfosalicyclic acid test (SSA); and quantification methods include the ratio of albumin or protein to creatinine and the 24-hour urine protein collection.


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