What is tubular proteinuria?

Updated: Mar 25, 2020
  • Author: Beje Thomas, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Answer

Tubular proteinuria is a result of tubulointersitial disease affecting the proximal renal tubules and interstitium.  This results in decreased proximal reabsorption of proteins—in particular, low molecular weight proteins (generally below 25,000 Daltons) such as beta-2 microglobulin. Under normal conditions these proteins are completely reabsorbed in the proximal tubules. The amount of proteinuria is usually


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