What are the physical findings characteristic of acute tubular necrosis (ATN)?

Updated: Mar 15, 2021
  • Author: Sangeeta Mutnuri, MBBS; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Physical examination findings are often unremarkable and acute kidney injury (AKI) is incidentally detected on routine laboratory studies (ie, elevated blood urea nitrogen [BUN] and creatinine levels).

Findings may suggest hypovolemia (eg, low jugular venous pressure, loss of skin turgor, orthostatic hypotension, dry mucous membranes, tachycardia) as a cause. Abdominal distension may raise the concern of intra-abdominal hypertension and compartment syndrome as a potential cause of ATN. Muscle tenderness could potentially be due to rhabdomyolysis, which can lead to ATN.

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