What is the role of linezolid in intravenous-to-oral switch therapy?

Updated: Jul 30, 2018
  • Author: Shirin A Mazumder, MD, FIDSA; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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In 2003, Li et al noted that intravenous linezolid can be followed by oral linezolid; these regimens were found to shorten hospital stays. [39] The exact timing of the switch depends on the clinical condition of the patient; oral and intravenous linezolid are relatively similar in effect. Linezolid is available in intravenous, film-coated tablet, and oral suspension forms. Linezolid can be assayed in serum and body fluids and has good bioavailability, with a maximum blood concentration at 0.5-2 hours.

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