What is the efficacy of cephalosporins in intravenous-to-oral switch therapy?

Updated: Jul 30, 2018
  • Author: Shirin A Mazumder, MD, FIDSA; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Similar switches can be effective with cephalosporins. Validated treatment algorithms, such as the Classification of Community-Acquired Pneumonia (CoCAP), now enable decisions concerning which patients with CAP require hospitalization and which patients will benefit from early switch therapy. Generally, unstable patients with CAP are suitable candidates for early switch therapy, which consists of rapid initiation of 1-2 days of intravenous therapy followed by 5 days of oral therapy, with early hospital discharge after the administration of 1-2 doses of oral antibiotic.

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