How is gonococcal arthritis treated?

Updated: Sep 03, 2019
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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As a rule, a 2-week course of intravenous antibiotics is sufficient to treat purulent gonococcal arthritis. Infected joints involved in the syndrome of disseminated gonococcemia often respond to 7-10 days of IV therapy. [36] Because of the high worldwide resistance rates to the quinolones (20%-100%), they should be used only when the particular isolate is sensitive to this class of antimicrobial. [42]

In addition, patients with gonococcal arthritis should receive concurrent therapy for chlamydia, such as one dose of 2 g of azithromycin or 7 days of doxycycline twice a week.

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