What are the treatment options for gram-negative joint infections of septic arthritis?

Updated: Sep 19, 2017
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Gram-negative native joint infections with a pathogen that is sensitive to quinolones can be treated with oral ciprofloxacin for the final 1-2 weeks of treatment. As a rule, a 2-week course of intravenous antibiotics is sufficient to treat gonococcal arthritis. [25] Because of the high worldwide resistance rates to the quinolones (20%-100%), they should be used only when the particular isolate is sensitive to this class of antimicrobial. [28]


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