What are the clinical features of viral septic arthritis?

Updated: Sep 19, 2017
  • Author: John L Brusch, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

Table 1, below, provides a summary of the clinical features of arthritis caused by various viral organisms.

Table 1. Clinical Features of Viral Disease–Associated Arthritis (Open Table in a new window)

Virus

Clinical Features of Viral Disease–Associated Arthritis

Parvovirus B19

Occurs in adult women with erythema infectiosum, often an itchy rash

Hepatitis A

Muscle aches and rash in 10% of cases

Hepatitis B

Onset in the preicteric phase; usually resolves as jaundice develops; chronic arthritis possible in patients with chronic hepatitis B infection

Hepatitis C

History similar to hepatitis B joint infection; usually associated with cryoglobulinemia

Rubella (natural infection and vaccine related)

Onset is possible before, during, or after the appearance of the rash; usually resolves in a few weeks; may recur and, more commonly, may persist

Human immunodeficiency virus [HIV] (2 types occur, both with noninflammatory, sterile joint fluid)

Develops over several days, and severe knee or ankle pain is characteristic; excellent response to nonsteroidal anti-inflammatory agents (NSAIDS)

Sudden onset of severe pain in the shoulders and elbows, closely resembling an acute gouty attack; Opiates often necessary to control pain

Mumps

Occurs in adult men 2 weeks after the presentation of parotitis


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