What is the prevalence of chronic fatigue syndrome (CFS)?

Updated: Aug 29, 2018
  • Author: Jefferson R Roberts, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Answer

CFS affects 836,000 to 2.5 million Americans. [1] An estimated 84%-91% of individuals with the condition have not been diagnosed; therefore, the true prevalence is unknown. Overall, CFS is more common in females than in males and occurs most commonly in young to middle-aged adults. [13] The average age of onset is 33 years, although cases have been reported in patients younger than 10 years and older than 70 years. Patients with CFS experience loss of productivity and high medical costs that contribute to a total economic burden of $17-24 billion annually. [1]


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