What are complications of nosocomial pneumonia?

Updated: Jul 30, 2018
  • Author: Burke A Cunha, MD; Chief Editor: John L Brusch, MD, FACP  more...
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Answer

Answer

Failure to successfully wean the patient from the respirator (possibly because of a lack of cardiopulmonary function or a superimposed process [eg, HSV-1 pneumonitis]) is a common problem following intubation for nosocomial pneumonia.

HSV-1 pneumonitis develops in intubated patients who have unchanging or persistent pulmonary infiltrates after 2 weeks of antimicrobial therapy. These patients usually have low-grade fevers with variable degrees of leukocytosis. Demonstrating HSV-1 in samples of respiratory secretions may establish the diagnosis.

Start treatment with acyclovir in patients diagnosed with HSV-1 infection; acyclovir decreases hypoxemia and subsequently permits weaning of the patient from the respirator.


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